They concluded that 1 C/S may be avoided for every 28 deliveries among low-risk nulliparas who undergo elective IOL at 39 weeks GA. They recommended that if eIOL option is not used, the patients should be informed of the higher likelihoods of developing hypertension/preeclampsia and of requiring a C/S when EM option is pursued. The rate of hypertension/preeclampsia was 9.1% in the IOL group vs. Neonatal death or severe neonatal complications occurred in 4.3% in IOL group vs. studied the perinatal consequences of IOL at 39 weeks GA among 6106 low-risk nulliparous women from 412 hospitals in an RCT parallel group, unmasked trial. Thus, preference modeling calculations revealed that 39-week eIOL was the preferred option over EM. 0.25% in EM ( p < 0.03), and neonatal morbidity was 9.4% in eIOL vs. The neonatal deaths were 0.12% in eIOL vs. While there were no differences in maternal mortality between the two groups (0% eIOL vs. When patients had an unfavorable cervix, eIOL at 39 weeks resulted in fewer C/S vs. C/S rates were statistically significantly higher in the EM arm (35.9 vs. EM with IOL at 41 weeks among undelivered patients. eIOL at 39 weeks resulted in fewer maternal and neonatal risks vs. reported on a Monte Carlo microsimulation model regarding eIOL at 39 weeks or expectant management (EM) with IOL for standard medical or obstetrical indications or at 41 weeks if undelivered. The number needed to treat to benefit (NNTB) with IOL in order to prevent 1 perinatal death was 410 (95% CI 322–1492). 160/1000 women with IOL and an increase in all-cause perinatal deaths vs. reported on 9383 patients from 22 trials and found that expectant management, until onset of labor up to 42 weeks GA, resulted in a higher C/S rate (180/1000 women) vs. in the expectant management group (1.7 vs. described results of a study wherein IOL at 41 weeks GA was compared to expectant management until 42 weeks GA. Although there were no significant differences in the C/S rates between the two groups (10.8% in both), there were fewer adverse perinatal outcomes (5-minute Apgar score <7, meconium aspiration) in IOL group vs.
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